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The Article in Brief
Detecting Hepatitis B and C by Combined Public Health and Primary Care Birth Cohort Testing
Jeanne Heil , and colleagues
Background Chronic hepatitis C and B virus infections do not usually have symptoms, so many infections remain undetected or are diagnosed at a late stage. In order to detect this hidden population, researchers set out to determine the diagnostic yield (test uptake and positivity rate) of a birth cohort testing strategy in identifyting hepatitis B and C viruses.
What This Study Found A strategy to test the general population for hepatitis B and C viruses in areas of high prevalence had high test uptake but did not detect hidden chronic hepatitis C infections. The study, a public health-primary care collaboration, sought to test individuals between 40 and 70 years of age (n = 6,743) in two Dutch hepatitis hotspots. All family physicians in the hotspots invited their patients to be tested, with implementation and follow-up by the regional public health service. Test uptake was higher than expected at 51 percent (n = 3,434), however no active/chronic hepatitis C infections were detected.
Implications
- This strategy, the authors surmise, could be effective in countries with higher rates of hepatitis or other infectious diseases, but is not recommended for low prevalence countries.