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Research ArticleOriginal Research

Loneliness in Primary Care Patients: A Prevalence Study

Rebecca A. Mullen, Sebastian Tong, Roy T. Sabo, Winston R. Liaw, John Marshall, Donald E. Nease, Alex H. Krist and John J. Frey
The Annals of Family Medicine March 2019, 17 (2) 108-115; DOI: https://doi.org/10.1370/afm.2358
Rebecca A. Mullen
1Department of Family Medicine, University of Colorado School of Medicine, Aurora, Colorado
MD, MPH
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  • For correspondence: rebecca.mullen@ucdenver.edu
Sebastian Tong
2Department of Family Medicine and Population Health, Virginia Commonwealth University, Richmond, Virginia
MD, MPH
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Roy T. Sabo
2Department of Family Medicine and Population Health, Virginia Commonwealth University, Richmond, Virginia
3Department of Biostatistics, Virginia Commonwealth University, Richmond, Virginia
PhD
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Winston R. Liaw
4Department of Health Systems and Population Heath Sciences, University of Houston, Houston, Texas
5Robert Graham Center Policy Studies in Family Medicine & Primary Care, Washington, DC
MD, MPH
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John Marshall
2Department of Family Medicine and Population Health, Virginia Commonwealth University, Richmond, Virginia
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Donald E. Nease Jr
1Department of Family Medicine, University of Colorado School of Medicine, Aurora, Colorado
MD
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Alex H. Krist
2Department of Family Medicine and Population Health, Virginia Commonwealth University, Richmond, Virginia
MD, MPH
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John J. Frey III
6Department of Family Medicine and Community Health, The University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin
MD
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Article Figures & Data

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  • Figure 1
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    Figure 1

    Percentage of responses to the 3-item UCLA Loneliness Scale (N = 1,235).

    UCLA = University of California, Los Angeles.

  • Figure 2
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    Figure 2

    Predicted loneliness score vs age (18-<90 y) (N = 1,235).

    Note: The black line illustrates a linear decrease in loneliness scores with increasing age and the gray area represents the 95% CI.

  • Figure 3
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    Figure 3

    Unadjusted odds ratios for participant characteristics and loneliness (N = 1,246).

    Note: Forest plot of the unadjusted odds ratio (black circles) and 95% CI (horizontal lines).

Tables

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    Table 1

    Patient Demographics By State Health System (N = 1,246)

    CharacteristicTotal
    (n = 1,246)
    Colorado
    (n = 535)
    Virginia
    (n = 611)
    Sex, No. (%)
     Male459 (37)238 (45)221 (31)
     Female781 (63)296 (55)485 (69)
    Age, No. (%), y
     <2558 (5)20 (4)38 (5)
     ≥25-<45369 (30)141 (27)228 (33)
     ≥45-<65492 (40)195 (37)297 (42)
     ≥65307 (25)168 (32)139 (20)
    Race and ethnicity, No. (%)
     White879 (71)426 (81)453 (64)
     Black204 (16)11 (2)193 (27)
     Hispanic81 (7)61 (12)20 (3)
     Asian33 (3)8 (2)25 (4)
     Native American14 (1)9 (2)5 (1)
     Other22 (2)12 (2)15 (2)
    Employment status, No. (%)
     Employed full time548 (45)231 (44)317 (45)
     Employed part time119 (10)40 (8)79 (11)
     Retired245 (20)128 (24)117 (17)
     Disabled131 (11)54 (10)77 (11)
     Homemaker62 (5)27 (5)35 (5)
     Unemployed64 (5)21 (4)43 (6)
     Student32 (3)12 (2)20 (3)
     Other23 (1)10 (2)13 (2)
     Prefer not to answer4 (0)0 (0)4 (1)
    Relationship status, No. (%)
     Married668 (54)307 (58)361 (51)
     Widowed/separated/divorced279 (22)109 (21)170 (24)
     Never married158 (13)59 (11)99 (14)
     In a relationship118 (10)49 (9)69 (10)
     Prefer not to answer16 (1)7 (1)9 (1)
    Location, No. (%)
     Urban956 (77)345 (65)611 (86)
     Rural287 (23)187 (35)100 (14)
    • Note: Percentage is of the total in each respective column. Colorado and Virginia samples were significantly different in every category (P values not displayed). Classifications with similar meanings (eg, widowed, separated, divorced) were combined for the purpose of analysis and therefore are illustrated similarly here.

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    Table 2

    Nonlonely and Lonely Respondents Health Status and Utilization (N = 1,226)

    Measure, mean (SD)Nonlonely (n = 982)Lonely (n = 244)OR (95% CI)aPAdj OR1 (95% CI)bPAdj OR2 (95% CI)cP
    Poor physical or mental health days4.2 (8.2)10.4 (11.1)1.06 (1.04-1.07)<.011.04 (1.02-1.06)<.011.05 (1.03-1.07)<.01
    Primary care visits3.0 (4.3)5.0 (7.0)1.07 (1.03-1.10)<.011.02 (0.99-1.05).171.04 (1.00-1.07).03
    ED/urgent care visits0.3 (1.0)0.5 (1.2)1.24 (1.12-1.38)<.011.09 (0.98-1.22).121.15 (1.04-1.28)<.01
    Hospitalizations0.8 (1.4)1.6 (2.2)1.15 (1.01-1.31).041.02 (0.88-1.17).821.08 (0.94-1.24).29
    • Adj = adjusted; ED = emergency department; OR = odds ration; SD = standard deviation.

    • Note: Poor health days are reported in past month, while utilization measures are numbered in past 12 months.

    • ↵a Odds ratios unadjusted for other patient factors.

    • ↵b Adj OR1 represents odds ratios adjusted for all patient factors (sex, age, race, employment, relationship, location, health).

    • ↵c Adj OR2 represents odds ratios adjusted only for patient demographics significantly associated with loneliness classification (employment, relationship).

Additional Files

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    Supplemental appendix

    Files in this Data Supplement:

    • Supplemental data: Appendix - PDF file
  • The Article in Brief

    Loneliness in Primary Care Patients: A Prevalence Study

    Rebecca A. Mullen , and colleagues

    Background Loneliness has important health consequences. However, little is known about loneliness in primary care patient populations. This study describes the prevalence of loneliness in patients presenting for primary care and its association with demographic factors, health care utilization, and health-related quality of life.

    What This Study Found Twenty percent of adult patients making routine primary care visits report being lonely, and the prevalence is higher in younger patients. A survey of 1,235 primary care patients in Colorado and Virginia found that 246 (20 percent) reported lack of companionship, feeling left out, and feelings of isolation from others. The prevalence of loneliness decreased with age, with 33 percent (18/58) of respondents less than 25 years old reporting loneliness compared to 11 percent (34/307) of those over 65 years old. Loneliness was significantly associated with relationship status and employment status. Respondents who were divorced, separated, widowed or never married, as well as those who were unemployed or disabled, had a significantly higher prevalence of loneliness than other respondents. People in poor health were more likely to report loneliness, and a high level of loneliness was positively associated with three measures of health care utilization: number of visits to the primary care office, number of hospitalizations, and number of emergency room or urgent care visits.

    Implications

    • These findings contribute to the growing body of evidence that loneliness is widespread and associated with poor health.
    • The authors call on primary care clinicians to prioritize social connections as they consider the risks and needs of lonely patients.
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The Annals of Family Medicine: 17 (2)
The Annals of Family Medicine: 17 (2)
Vol. 17, Issue 2
March/April 2019
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Loneliness in Primary Care Patients: A Prevalence Study
Rebecca A. Mullen, Sebastian Tong, Roy T. Sabo, Winston R. Liaw, John Marshall, Donald E. Nease, Alex H. Krist, John J. Frey
The Annals of Family Medicine Mar 2019, 17 (2) 108-115; DOI: 10.1370/afm.2358

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Loneliness in Primary Care Patients: A Prevalence Study
Rebecca A. Mullen, Sebastian Tong, Roy T. Sabo, Winston R. Liaw, John Marshall, Donald E. Nease, Alex H. Krist, John J. Frey
The Annals of Family Medicine Mar 2019, 17 (2) 108-115; DOI: 10.1370/afm.2358
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Subjects

  • Domains of illness & health:
    • Mental health
  • Person groups:
    • Older adults
    • Vulnerable populations
  • Methods:
    • Quantitative methods
  • Other research types:
    • Health services
  • Core values of primary care:
    • Personalized care
    • Relationship
  • Other topics:
    • Social / cultural context
    • Patient perspectives

Keywords

  • loneliness
  • 3-item UCLA Loneliness Scale
  • primary care
  • prevalence

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