Article Figures & Data
Tables
- Table 1.
Prevalence of Staphylococcus aureus Carriage in the US Population Based on Demographic Characteristics
Characteristic Persons No. (%) P Value * In which a score >1.00 indicates the official poverty threshold. Age, y 1–6 5,727,630 (25.62) < .01 7–19 21,750,247 (41.76) 20–64 51,795,838 (31.50) ≥ 65 7,633,096 (26.02) Race/ethnicity Non-Hispanic white 60,714,994 (32.91) < .01 Non-Hispanic black 8,640,926 (26.78) Hispanic 13,816,245 (34.19) Other 3,734,645 (33.87) Sex Male 48,339,253 (37.02) < .01 Female 38,567,558 (28.02) Place of birth United States 76,736,750 (32.38) .03 Mexico 2,866,928 (27.26) Elsewhere 7,182,631 (35.04) Poverty-income ratio* < 1 12,960,604 (30.86) .20 ≥ 1 69,309,681 (32.92) - Table 2.
Prevalence of Staphylococcus aureus Carriage in the US Population Based on Clinical Characteristics
Characteristic Persons No. (%) P Value General health status Good-excellent 76,339,026 (32.59) .40 Poor-fair 10,567,785 (31.17) Number of outpatient visits in past year 0 14,873,280 (35.07) .09 ≥ 1 71,975,850 (31.89) Hospitalization in the past Yes 7,256,430 (30.04) .38 No 79,650,380 (32.64) Use of antibiotics in past 30 days Yes 4,769,010 (24.43) .01 No 82,137,800 (33.03) Oral health Good to very good 61,288,546 (32.80) .78 Poor to fair 25,047,076 (32.22) Current smoker or smoker in the household Yes 21,806,172 (29.03) .02 No 64,487,150 (33.83) Diabetes Yes 3,936,552 (30.22) .52 No 82,970,259 (32.52) Asthma Yes 11,918,406 (36.35) .04 No 74,901,009 (31.86) - Table 3.
Logistic Regression Analysis Predicting Carriage of Staphylococcus aureus in the US Population
Characteristic Odds Ratio (95% CI) CI = confidence interval. Age, y 1–6 0.74 (0.63–0.87) 7–19 1.53 (1.36–1.73) 20–64 1.00 ≥ 65 0.73 (0.59–0.91) Race/ethnicity Non-Hispanic white 1.00 Non-Hispanic black 0.71 (0.61–0.83) Hispanic 1.07 (0.93–1.24) Other 0.94 (0.64–1.37) Sex Male 1.00 Female 0.66 (0.56–0.78) Place of birth United States 1.00 Mexico 0.67 (0.54–0.82) Elsewhere 1.11 (0.89–1.39) Use of antibiotics in past 30 d Yes 0.63 (0.45–0.88) No 1.00 Current smoker or smoker in the household Yes 0.78 (0.65–0.95) No 1.00 Asthma Yes 1.24 (1.03–1.51) No 1.00
Additional Files
The Article in Brief
Background Staphylococcus aureus is a common cause of invasive infection, often found in hospitals and other institutional settings. A drug-resistant strain called methicillin-resistant S aureus (MRSA) has been increasingly found outside the hospital setting. This study estimates the prevalence of S aureus and MRSA in the general population of the United States.
What This Study Found An estimated 86.9 million people, or nearly one-third of the US population, carry S aureus. More than 2.2 million people, or less than 1 percent of the population, carry MRSA. Teens and males are more likely than other groups to carry S. aureus. When elderly patients carry S aureus, they are more likely than younger people to carry MRSA.
Implications
- Avoiding overuse of antibiotics is important to slow the spread of resistant organisms, such as MRSA.
- Clinicians should take infection control procedures that are effective against S aureus, particularly when treating teen and male patients.
- Elderly patients with suspected staphylococcus infections may need antibiotic coverage against resistant strains.
- The authors advise clinicians making therapeutic decisions to monitor bacterial carriage rates and resistance patterns for their own hospitals and cities, in addition to the patterns identified in thi