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Research ArticleOriginal Research

Exploring and Validating Patient Concerns: Relation to Prescribing for Depression

Ronald M. Epstein, Cleveland G. Shields, Peter Franks, Sean C. Meldrum, Mitchell Feldman and Richard L. Kravitz
The Annals of Family Medicine January 2007, 5 (1) 21-28; DOI: https://doi.org/10.1370/afm.621
Ronald M. Epstein
MD
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Cleveland G. Shields
PhD
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Peter Franks
MD
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Sean C. Meldrum
MS
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Mitchell Feldman
MD, MPhil
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Richard L. Kravitz
MD, MSPH
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  • Figure 1.
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    Figure 1.

    Study design.

    Six standardized clinical portrayals were created by crossing 2 condition roles (major depression or adjustment disorde)r with 3 drug request types (brand-specific, general, or none).

  • Figure 2.
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    Figure 2.

    Patients’ receipt of prescriptions for antidepressant medications by clinical role, EVC score, and request condition.

    EVC = exploration and validation of patient concerns.

Tables

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    Table 1.

    Types of Requests and Clinical Roles in the Study

    Request TypeMajor Depression RoleAdjustment Disorder Role
    Note: A through F indicate the 6 standardized portrayals obtained by combining the request type and clinical role; numbers of visits for each portrayal are given in Figure 1.
    Brand-specific request driven by direct-to-consumer advertisement: “I saw this ad on TV the other night. It was about Paxil. Some things about the ad really struck me. I was wondering if you thought Paxil might help me.”AD
    General request driven by informational television show: “I was watching this TV program about depression the other night. It really got me thinking. I was wondering if you thought a medicine might help me.”BE
    No request (symptoms only)CF
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    Table 2.

    Characteristics of Participating Physicians

    CharacteristicMean (SD; Range) or No. (%)
    HMO = health maintenance organization.
    Note: N = 152, but numbers of physicians do not total 152 because of missing data.
    Age, years46.2 (9.9; 30–81)
    Time in practice, years17.4 (9.6; 4–49)
    Sex
        Male101 (67.8)
        Female48 (32.2)
    Specialty
        Family physician49 (32.7)
        Internal medicine101 (67.3)
    Type of practice
        HMO33 (22.1)
        Group61 (40.9)
        Solo37 (24.8)
        Academic18 (12.1)
    Study site
        Sacramento, Calif51 (34.2)
        Rochester, NY48 (32.2)
        San Francisco, Calif50 (33.6)
    Race/ethnicity
        African American3 (2.0)
        Asian/Pacific Islander32 (21.3)
        Hispanic/Latino5 (3.3)
        Other4 (2.7)
        White105 (70.0)
        Missing1 (0.7)
    • View popup
    Table 3.

    Examples of Statements Coded as Cutoff, Preliminary Exploration, Further Exploration, and Validation

    TranscriptCoding of the Statement
    EVC = exploration and validation of patient concerns; Dr = physician; Pt = patient.
    Physician-patient sequences with low EVC score
    Back pain
        Dr: So, what brings you in today?
        Pt: My back has been bothering me.Patient expresses a concern
        Dr: What kind of work do you do?Coded as Cutoff: physician does not respond to the concern and changes the topic
        Pt: Um, well, I was an administrative assistant as of the beginning of January, but I got laid off, so …Patient expresses another concern
        Dr: So, recently laid off.Coded as Preliminary Exploration: missed an opportunity to validate the patient’s concerns
        Pt: Yes.
        Dr: Okay. Okay. And when was your last physical exam, like pelvic exam, breast exam, all that?Not coded: physician again redirects the conversation, thus response is not scored as Further Exploration; Cutoff coded only once for each patient concern
    Mood
        Pt: I’ve been feeling tired all the time.Patient expresses a concern
        Dr: How’s your sleep?Not coded yet: no acknowledgment or exploration of patient’s experience of tiredness, but asks about a possible cause of tiredness
        Pt: I can’t fall asleep.
        Dr: Do you cry very much?Coded as Cutoff: cuts off patient and switches topic to something related in the physician’s mind, but not necessarily to the patient
        Pt: Once in a while.
        Dr: Do you feel hopeless?Does not explore patient’s concerns and switches topics; Cutoff coded only once for each patient concern
    Physician-patient sequences with high EVC score
    Back pain
        Dr: So, what brings you in today?
        Pt: My back has been bothering me.Patient states a concern
        Dr: How so?Coded as Preliminary Exploration
        Pt: When I bend over it hurts, and I’m stiff in the morning.Describes in more detail
        Dr: Do you remember when it started?Coded as Further Exploration of the patient’s concerns
        Pt: Yes. I was moving boxes in my house.Gives more information
        Dr: What did it feel like when it started hurting?More exploration; Further Exploration coded only once for each patient concern
        Pt: It didn’t start hurting until the next day.Gives more information
        Dr: Back pain is pretty annoying, isn’t it?Coded as Validation: validates patient’s concerns by speaking to her underlying emotions
        Pt: It sure is.
    Mood
        Pt: I got laid off when my company moved.Patient expresses a concern
        Dr: Oh, I’m sorry to hear that.Coded as Validation because of expressed empathy
        Pt: I could have moved with the company and continued my job, but I didn’t want to move.Expresses more concern
        Dr: That must have been a difficult decision for you.Again, validates the patient’s experience, but Validation coded only once for each patient concern
        Pt: It was, I sometimes wonder if I made the right choice.Reveals more information
    • View popup
    Table 4.

    Logistic Regression Analysis Stratified by EVC Score

    EffectOdds Ratio (95% CI)
    Note: Showing the effect of clinical role and request for medication on prescribing of antidepressants. Controlled for study site (Rochester, Sacramento, San Francisco), physician age, and physician sex.
    EVC = exploration and validation of patient concerns; CI = confidence interval.
    * Major depression vs adjustment disorder.
    † Any vs none.
    ‡ P ≤ .005.
    Low EVC score (lowest tercile)
        Depression role*1.82 (0.33–9.89)
        Request for medication†43.54 (1.69–1,120.87)‡
    High EVC score (upper 2 terciles)
        Depression role*4.70 (2.18–10.16)‡
        Request for medication†4.02 (1.67–9.68)‡

Additional Files

  • Figures
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  • The Article in Brief

    Exploring and Validating Patient Concerns: Relation to Prescribing for Depression

    Ronald M. Epstein, MD , and colleagues

    Background There are inconsistencies in the prescription of antidepressants in the primary care office. Some patients with major depression do not receive medications while others with less clear symptoms do. This study set out to understand the relationship between the ways in which patients and doctors communicate and decisions to prescribe depression medications.

    What This Study Found When doctors explore and confirm patient concerns--including patient symptoms, ideas, expectations, ability to function, and feelings�they are more likely to prescribe antidepressants for patients who will likely benefit from them, and less likely to prescribe them for patients whose need for the medication is not clear.

    Implications

    • Exploring and validating patient concerns is linked to quality of care for depression.
    • This is one of the first published studies to link doctors� communication with appropriateness of prescribing medication.
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The Annals of Family Medicine: 5 (1)
The Annals of Family Medicine: 5 (1)
Vol. 5, Issue 1
1 Jan 2007
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Exploring and Validating Patient Concerns: Relation to Prescribing for Depression
Ronald M. Epstein, Cleveland G. Shields, Peter Franks, Sean C. Meldrum, Mitchell Feldman, Richard L. Kravitz
The Annals of Family Medicine Jan 2007, 5 (1) 21-28; DOI: 10.1370/afm.621

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Exploring and Validating Patient Concerns: Relation to Prescribing for Depression
Ronald M. Epstein, Cleveland G. Shields, Peter Franks, Sean C. Meldrum, Mitchell Feldman, Richard L. Kravitz
The Annals of Family Medicine Jan 2007, 5 (1) 21-28; DOI: 10.1370/afm.621
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