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Research ArticleOriginal Research

Developing a Clinician Friendly Tool to Identify Useful Clinical Practice Guidelines: G-TRUST

Allen F. Shaughnessy, Akansha Vaswani, Bonnie K. Andrews, Deborah R. Erlich, Frank D’Amico, Joel Lexchin and Lisa Cosgrove
The Annals of Family Medicine September 2017, 15 (5) 413-418; DOI: https://doi.org/10.1370/afm.2119
Allen F. Shaughnessy
1Tufts University School of Medicine, Boston, Massachusetts
PharmD, MMedEd
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  • For correspondence: Allen.Shaughnessy@tufts.edu
Akansha Vaswani
2Department of Counseling and School Psychology, University of Massachusetts, Boston, Massachusetts
MS
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Bonnie K. Andrews
2Department of Counseling and School Psychology, University of Massachusetts, Boston, Massachusetts
MPH
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Deborah R. Erlich
1Tufts University School of Medicine, Boston, Massachusetts
MD, MMedEd
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Frank D’Amico
3McAnulty College and Graduate School of Liberal Arts, Duquesne University, Pittsburgh, Pennsylvania
PhD
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Joel Lexchin
4School of Health Policy and Management, York University, Toronto, Canada
MD
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Lisa Cosgrove
2Department of Counseling and School Psychology, University of Massachusetts, Boston, Massachusetts
PhD
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    Figure 1

    Study flow chart.

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    Table 1

    Demographic Composition of the Expert Panel

    CharacteristicNo. (%)
    Background
     Evidence-based medicine expert22 (55)
     Guideline developer17 (42.5)
     Consumer representative1 (2.5)
    Sex
     Male26 (65)
     Female14 (35)
    Self-identified background
     Clinician16 (40)
     Methodologist17 (42.5)
     Methodologist/clinician6 (15)
     Consumer representative1 (2.5)
    Geography
     Europe8 (20)
     United Kingdom4 (10)
     Canada4 (10)
     United States21 (52.5)
     South America1 (2.5)
     Africa1 (2.5)
     Asia1 (2.5)
    Organization
     Academia/university20 (50)
     Government8 (20)
     Nongovernmental, nonacademic4 (10)
     Industry3 (7.5)
     Professional society5 (12.5)
    Identification method
     Evidence-based medicine listserve15 (38)
     Guideline developers9 (23)
     Author contacts16 (40)
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    Table 2

    Final Item Wording With Utility Scores and Ratings

    Final Item WordingMedian Utility ScoreaRating Item as Major Threat %
    Relevance threats
     1. The patient populations and conditions are relevant to my clinical setting.15.729.4
     2. The recommendations are clear and actionable.11.235.3
     3. The recommendations focus on improving patient-oriented outcomes, explicitly comparing benefits versus harms to support clinical decision making.18.082.4
    Evidence threats
     4. The guidelines are based on a systematic review of the research data.22.5100.0
     5. The recommendation statements important to you are based on graded evidence and include a description of the quality (e,g, strong, weak) of the evidence.20.285.3
     6. The guideline development includes a research analyst, such as a statistician or epidemiologist.2.326.5
    Interpretation threats
     7. The Chair of the guideline development committee and a majority of the rest of the committee are free of declared financial conflicts of interest, and the guideline development group did not receive industry funding for developing the guideline.3.447.1
     8. The guideline development includes members from the most relevant specialties and includes other key stakeholders, such as patients, payer organizations, and public health entities, when applicable.6.741.2
    • ↵a Ranked from 0 to 100, with higher scores indicating greater utility.

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  • The Article in Brief

    Developing a Clinician Friendly Tool to Identify Useful Clinical Practice Guidelines: G-TRUST

    Allen F. Shaughnessy , and colleagues

    Background Although clinical practice guidelines should be based on high quality research and practice experience, they vary in their relevance to practice, use of evidence, and other factors. This report describes the development of the Guideline Trustworthiness, Relevance, and Utility Scoring Tool (G-TRUST), a tool for clinicians to identify useful practice guidelines.

    What This Study Found The 8-item G-TRUST is potentially helpful in identifying useful clinical practice guidelines.Twenty-two experts in evidence-based medicine, 17 developers of high-quality guidelines, and one consumer representative participated in a process to obtain consensus on a checklist of items and their relative impact on guideline quality. More than 75 percent of experts found three of the eight checklist items to be major indicators of guideline usefulness and, in comparison to a reference standard (the AGREE tool), a scoring system was developed identifying guidelines as "useful," "may not be useful," and "not useful." The checklist identified 92 percent of low-quality guidelines and disqualified many high quality guidelines because of a stricter definition of trustworthiness, including more stringent conflict of interest requirements.

    Implications

    • With the proliferation of practice guidelines, numbering in the thousands, the authors call for research to determine the reliability of G-TRUST and to examine how the tool might interact with technology, such as smart phone applications
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The Annals of Family Medicine: 15 (5)
The Annals of Family Medicine: 15 (5)
Vol. 15, Issue 5
September/October 2017
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Developing a Clinician Friendly Tool to Identify Useful Clinical Practice Guidelines: G-TRUST
Allen F. Shaughnessy, Akansha Vaswani, Bonnie K. Andrews, Deborah R. Erlich, Frank D’Amico, Joel Lexchin, Lisa Cosgrove
The Annals of Family Medicine Sep 2017, 15 (5) 413-418; DOI: 10.1370/afm.2119

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Developing a Clinician Friendly Tool to Identify Useful Clinical Practice Guidelines: G-TRUST
Allen F. Shaughnessy, Akansha Vaswani, Bonnie K. Andrews, Deborah R. Erlich, Frank D’Amico, Joel Lexchin, Lisa Cosgrove
The Annals of Family Medicine Sep 2017, 15 (5) 413-418; DOI: 10.1370/afm.2119
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  • Un outil modifie, concu pour faciliter le choix des lignes directrices: Une version simplifiee de G-Trust (un outil devaluation de la fiabilite, de la pertinence et de lutilite des lignes directrices) a lintention des medecins en pratique
  • Modified tool designed to ease guideline choices: Simplified version of Guideline Trustworthiness, Relevance, and Utility Scoring Tool (G-TRUST) for physicians in practice
  • Becoming a Phronimos: Evidence-Based Medicine, Clinical Decision Making, and the Role of Practical Wisdom in Primary Care
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  • Addressing barriers to evidence-based medicine in pediatric surgery: an introduction to the Canadian Association of Paediatric Surgeons Evidence-Based Resource
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  • Validation des lignes directrices de pratique clinique: Criteres du College des medecins de famille du Canada
  • Gestion des conflits dinterets durant lelaboration de lignes directrices en sante
  • Managing conflicts of interest in the development of health guidelines
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