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Research ArticleOriginal Research

Proactive Deprescribing Among Older Adults With Polypharmacy: Barriers and Enablers

Kenya Ie, Reiko Machino, Steven M. Albert, Shiori Tomita, Hiroki Ohashi, Iori Motohashi, Takuya Otsuki, Yoshiyuki Ohira and Chiaki Okuse
The Annals of Family Medicine May 2025, 23 (3) 207-213; DOI: https://doi.org/10.1370/afm.240363
Kenya Ie
1Department of General Internal Medicine, Kawasaki Municipal Tama Hospital, Shukugawara, Tama Ward, Kawasaki, Kanagawa, Japan
2Department of General Internal Medicine, St Marianna University School of Medicine, Miyamae-ku, Kawasaki, Kanagawa, Japan
MD, MPH, PhD
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  • For correspondence: iekenya0321@gmail.com
Reiko Machino
1Department of General Internal Medicine, Kawasaki Municipal Tama Hospital, Shukugawara, Tama Ward, Kawasaki, Kanagawa, Japan
2Department of General Internal Medicine, St Marianna University School of Medicine, Miyamae-ku, Kawasaki, Kanagawa, Japan
PharmD
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Steven M. Albert
3Department of Behavioral and Community Health Sciences, University of Pittsburgh, School of Public Health, Pittsburgh, Pennsylvania
PhD, MA, MS
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Shiori Tomita
4Tama Family Clinic, Tama Ward, Kawasaki, Kanagawa, Japan
MD, PhD
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Hiroki Ohashi
4Tama Family Clinic, Tama Ward, Kawasaki, Kanagawa, Japan
MD
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Iori Motohashi
1Department of General Internal Medicine, Kawasaki Municipal Tama Hospital, Shukugawara, Tama Ward, Kawasaki, Kanagawa, Japan
2Department of General Internal Medicine, St Marianna University School of Medicine, Miyamae-ku, Kawasaki, Kanagawa, Japan
MD, MPH
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Takuya Otsuki
1Department of General Internal Medicine, Kawasaki Municipal Tama Hospital, Shukugawara, Tama Ward, Kawasaki, Kanagawa, Japan
2Department of General Internal Medicine, St Marianna University School of Medicine, Miyamae-ku, Kawasaki, Kanagawa, Japan
MD, PhD
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Yoshiyuki Ohira
2Department of General Internal Medicine, St Marianna University School of Medicine, Miyamae-ku, Kawasaki, Kanagawa, Japan
MD, PhD
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Chiaki Okuse
1Department of General Internal Medicine, Kawasaki Municipal Tama Hospital, Shukugawara, Tama Ward, Kawasaki, Kanagawa, Japan
2Department of General Internal Medicine, St Marianna University School of Medicine, Miyamae-ku, Kawasaki, Kanagawa, Japan
MD, PhD
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Article Information

vol. 23 no. 3 207-213
DOI 
https://doi.org/10.1370/afm.240363

Published By 
The Annals of Family Medicine
Print ISSN 
1544-1709
Online ISSN 
1544-1717
History 
  • Received for publication August 1, 2024
  • Revision received December 12, 2024
  • Accepted for publication January 6, 2025
  • Published online May 27, 2025.

Copyright & Usage 
© 2025 Annals of Family Medicine, Inc.

Author Information

  1. Kenya Ie, MD, MPH, PhD1,2⇑,
  2. Reiko Machino, PharmD1,2,
  3. Steven M. Albert, PhD, MA, MS3,
  4. Shiori Tomita, MD, PhD4,
  5. Hiroki Ohashi, MD4,
  6. Iori Motohashi, MD, MPH1,2,
  7. Takuya Otsuki, MD, PhD1,2,
  8. Yoshiyuki Ohira, MD, PhD2 and
  9. Chiaki Okuse, MD, PhD1,2
  1. 1Department of General Internal Medicine, Kawasaki Municipal Tama Hospital, Shukugawara, Tama Ward, Kawasaki, Kanagawa, Japan
  2. 2Department of General Internal Medicine, St Marianna University School of Medicine, Miyamae-ku, Kawasaki, Kanagawa, Japan
  3. 3Department of Behavioral and Community Health Sciences, University of Pittsburgh, School of Public Health, Pittsburgh, Pennsylvania
  4. 4Tama Family Clinic, Tama Ward, Kawasaki, Kanagawa, Japan
  1. CORRESPONDING AUTHOR: Kenya Ie, Department of General Internal Medicine, Kawasaki Municipal Tama Hospital, 1-30-37 Shukugawara, Tama-ku, Kawasaki, Kanagawa 214-8525, Japan, iekenya0321{at}gmail.com

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The Annals of Family Medicine: 23 (3)
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Proactive Deprescribing Among Older Adults With Polypharmacy: Barriers and Enablers
Kenya Ie, Reiko Machino, Steven M. Albert, Shiori Tomita, Hiroki Ohashi, Iori Motohashi, Takuya Otsuki, Yoshiyuki Ohira, Chiaki Okuse
The Annals of Family Medicine May 2025, 23 (3) 207-213; DOI: 10.1370/afm.240363

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Proactive Deprescribing Among Older Adults With Polypharmacy: Barriers and Enablers
Kenya Ie, Reiko Machino, Steven M. Albert, Shiori Tomita, Hiroki Ohashi, Iori Motohashi, Takuya Otsuki, Yoshiyuki Ohira, Chiaki Okuse
The Annals of Family Medicine May 2025, 23 (3) 207-213; DOI: 10.1370/afm.240363
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Keywords

  • polypharmacy
  • deprescribing
  • potentially inappropriate medication
  • chronic illness
  • aged
  • patient-centered care
  • decision making
  • physician-patient relationship
  • primary care

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