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Research ArticleOriginal Research

Incidence and Predictors of Hypertension Among Rural Chinese Adults: Results From Liaoning Province

Zhaoqing Sun, Liqiang Zheng, Robert Detrano, Xingang Zhang, Changlu Xu, Jue Li, Dayi Hu and Yingxian Sun
The Annals of Family Medicine January 2010, 8 (1) 19-24; DOI: https://doi.org/10.1370/afm.1018
Zhaoqing Sun
MS
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Liqiang Zheng
MS
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Robert Detrano
MD, PhD
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Xingang Zhang
MD
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Changlu Xu
MS
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Jue Li
MD
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Dayi Hu
MD
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Yingxian Sun
MD, PhD
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Article Figures & Data

Tables

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    • View popup
    Table 1.

    Baseline Characteristics of Study Participants

    Risk FactorMen (n=12,300)Women (n=12,060)PValue
    BP = blood pressure; BMI = body mass index.
    Age, mean (SD), y48.21 (10.36)47.86 (10.30).008
    Mongolian, %18.019.4.014
    High school education, %6.34.8<.001
    Income, %.023
        Income 1, <¥1,000/y33.534.6
        Income 2, ¥1,000 – ¥1,500/y12.813.5
        Income 3, ¥1,500 – ¥2,000/y15.115.1
        Income 4, >¥2,000/y38.636.9
    Physical activity, %<.001
        Low20.628
        Moderate45.545.4
        High33.926.6
    Current smoker, %66.914.2<.001
    Current drinker, %56.04.8<.001
    Family history of hypertension, %11.08.1<.001
    Systolic BP, mean (SD), mm Hg122.90 (10.06)119.37 (11.35)<.001
    Diastolic BP, mean (SD), mm Hg76.86 (7.24)75.26 (7.75)<.001
    Prehypertension, %77.164.1<.001
    BMI, mean (SD), kg/m222.89 (2.66)23.12 (3.05)<.001
    Salt intake, mean (SD), g/d15.61 (12.55)15.29 (12.16).043
    • View popup
    Table 2.

    Cumulative Incidence of Hypertension by Sex and Age-Group Among Rural Chinese

    MenWomen
    CharacteristicCase nIncidence %Case nIncidence %
    a The difference is statistically significant (P <.05).
    Age-group, years
        35–441,21522.088415.8
        45–541,20232.291325.0
        55–6476937.662533.3
        >6545345.239742.6
        P value<.05<.05
    Race
        Mongolian85238.571730.7
        Han2,75127.72,05221.5
        P value<.05<.05
    Baseline blood pressure status
        Prehypertension2,91730.82,02926.2
        Normal72225.679018.3
        P value<.05<.05
    Total3,63929.6a2,81923.4
    • View popup
    Table 3.

    Age-Adjusted Incidence of Hypertension in Men and Women of Rural China

    CharacteristicMen Incidence per 100/y (95% CI)Women Incidence per 100/y (95% CI)
    CI=confidence interval.
    Age-group, years
        35–449.52 (9.01–10.04)6.78 (6.36–7.23)
        45–5413.80 (13.08–14.54)10.74 (10.09–11.42)
        55–6416.27 (15.23–17.35)14.45 (13.41–15.53)
        >6518.57 (17.05–20.17)17.95 (16.37–19.61)
        P value<.05<.05
    Baseline blood pressure status
        Prehypertension13.24 (12.79–13.69)11.22 (10.77–11.69)
        Normal11.08 (10.33–11.86)7.90 (7.38–8.45)
        Total12.75 (12.74–13.14)10.04 (9.69–10.41)
    • View popup
    Table 4.

    Adjusted Hazards Ratio for Hypertension in Men and Women of Rural China

    MenWomen
    PredictorsHazard Ratio (95% CI)PValueHazard Ratio (95% CI)PValue
    CI=confidence interval.
    Age1.11 (1.10–1.13)<.0011.13 (1.11–1.15)<.001
    Education
        Not high school graduate1.00 (reference)1.00 (reference)
        High school graduate1.00 (0.88–1.13).9600.87 (0.73–1.03).103
    Annual mean income
        Income 1, <¥1,000/y1.00 (reference)1.00 (reference)
        Income 2, ¥1,000 – ¥1,500/y1.03 (0.92–1.15).5840.99 (0.88–1.12).927
        Income 3, ¥1,500 – ¥2,000/y1.10 (1.00–1.22).0451.09 (0.98–1.22).118
        Income 4, >¥2,000/y1.11 (1.03–1.20).0071.06 (0.97–1.16).183
    Physical activity
        High1.00 (reference)1.00 (reference)
        Moderate0.86 (0.80–0.92)<.0011.04 (0.95–1.15).408
        Low1.09 (0.99–1.21).0791.45 (1.30–1.61)<.001
    Ethnicity
        Han1.00 (reference)1.00 (reference)
        Mongolian1.09 (1.01–1.18).0321.16 (1.06–1.26).001
    Smoking
        Nonsmoker1.00 (reference)1.00 (reference)
        Current smoker1.00 (0.93–1.08).9760.95 (0.86–1.06).375
    Alcohol drinking
        Nondrinker1.00 (reference)1.00 (reference)
        Current drinker1.14 (1.06–1.23)<.0011.12 (0.94–1.32).194
    Body mass index, kg/m2
        <251.00 (reference)1.00 (reference)
        ≥251.28 (1.17–1.40)<.0011.45 (1.33–1.58)<.001
    Family history of hypertension
        No1.00 (reference)1.00 (reference)
        Yes1.14 (1.03–1.27).0131.39 (1.22–1.58)<.001
    Salt intake, g/d1.00 (1.00–1.01).0451.01 (1.00–1.01)<.001
    Baseline blood pressure status
        Normotentive1.00 (reference)1.00 (reference)
        Prehypertensive1.18 (1.08–1.28)<.0011.25 (1.15–1.36)<.001
    • View popup
    Table 5.

    Annual Incidence of Hypertension in Prior Chinese Studies and in the United States and Canada.

    Country1980–1990 %1990–2000 %After 2000 %
    China2.3–5.23.7–
    Canada–2.63.2
    United States–4.0–9.3–
    Current study––11.4

Additional Files

  • Tables
  • The Article in Brief

    Incidence and Predictors of Hypertension Among Rural Chinese Adults: Results From Liaoning Province

    Zhaoqing Sun , and colleagues

    Background Cardiovascular disease, including both stroke and heart disease, is the leading cause of death among Chinese adults. Hypertension, or high blood pressure, is an important risk factor for these conditions. This study set out to determine the percentage of new cases of hypertension appearing in China each year, to help assess how quickly it is spreading, and to determine what steps might be needed to control the disease.

    What This Study Found There is a high incidence of hypertension among rural Chinese adults. During a period of 28 months from 2004-2006 to 2008, more than 1in 4 adults developed hypertension. Most of these cases were untreated (80 percent) and uncontrolled (98 percent).

    Implications

    • The annual hypertension incidence of 11.4 percent is higher than that previously reported in China, Canada, or the United States.
    • Increases in hypertension are probably related to rapid social changes in China and may apply to other areas of the developing world.
    • The authors call for urgent public health measures to prevent and control hypertension.
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The Annals of Family Medicine: 8 (1)
The Annals of Family Medicine: 8 (1)
Vol. 8, Issue 1
1 Jan 2010
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Incidence and Predictors of Hypertension Among Rural Chinese Adults: Results From Liaoning Province
Zhaoqing Sun, Liqiang Zheng, Robert Detrano, Xingang Zhang, Changlu Xu, Jue Li, Dayi Hu, Yingxian Sun
The Annals of Family Medicine Jan 2010, 8 (1) 19-24; DOI: 10.1370/afm.1018

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Incidence and Predictors of Hypertension Among Rural Chinese Adults: Results From Liaoning Province
Zhaoqing Sun, Liqiang Zheng, Robert Detrano, Xingang Zhang, Changlu Xu, Jue Li, Dayi Hu, Yingxian Sun
The Annals of Family Medicine Jan 2010, 8 (1) 19-24; DOI: 10.1370/afm.1018
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