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Research ArticleORIGINAL RESEARCH

Reducing Readmission of Hospitalized Patients With Depressive Symptoms: A Randomized Trial

Suzanne E. Mitchell, Matthew Reichert, Jessica Martin Howard, Katherine Krizman, Alexa Bragg, Molly Huffaker, Kimberly Parker, Mary Cawley, Hannah Webb Roberts, Yena Sung, Jennifer Brown, Larry Culpepper, Howard J. Cabral and Brian W. Jack
The Annals of Family Medicine May 2022, 20 (3) 246-254; DOI: https://doi.org/10.1370/afm.2801
Suzanne E. Mitchell
1Department of Family Medicine, Boston University School of Medicine, Boston, Massachusetts
2Department of Family Medicine, Boston Medical Center, Boston, Massachusetts
3Department of Family Medicine, University of Massachusetts Medical School, Worcester, Massachusetts
MD, MSc
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  • For correspondence: Suzanne.Mitchell@bmc.org
Matthew Reichert
2Department of Family Medicine, Boston Medical Center, Boston, Massachusetts
4Department of Government, Harvard University, Cambridge, Massachusetts
MA
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Jessica Martin Howard
1Department of Family Medicine, Boston University School of Medicine, Boston, Massachusetts
MA, MPH
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Katherine Krizman
1Department of Family Medicine, Boston University School of Medicine, Boston, Massachusetts
LMHC, LPCC
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Alexa Bragg
1Department of Family Medicine, Boston University School of Medicine, Boston, Massachusetts
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Molly Huffaker
2Department of Family Medicine, Boston Medical Center, Boston, Massachusetts
JD
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Kimberly Parker
1Department of Family Medicine, Boston University School of Medicine, Boston, Massachusetts
MS, PMP
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Mary Cawley
1Department of Family Medicine, Boston University School of Medicine, Boston, Massachusetts
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Hannah Webb Roberts
2Department of Family Medicine, Boston Medical Center, Boston, Massachusetts
MPH, MSN
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Yena Sung
2Department of Family Medicine, Boston Medical Center, Boston, Massachusetts
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Jennifer Brown
5Department of Psychiatry, Mount Auburn Hospital, Cambridge, Massachusetts
MD
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Larry Culpepper
1Department of Family Medicine, Boston University School of Medicine, Boston, Massachusetts
MD, MPH
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Howard J. Cabral
6Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts
PhD
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Brian W. Jack
1Department of Family Medicine, Boston University School of Medicine, Boston, Massachusetts
2Department of Family Medicine, Boston Medical Center, Boston, Massachusetts
MD
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  • RE: Reducing Readmission of Hospitalized Patients With Depressive Symptoms: A Randomized Trial
    Sydney P. Stein and Melissa Garibotti
    Published on: 24 October 2022
  • Published on: (24 October 2022)
    Page navigation anchor for RE: Reducing Readmission of Hospitalized Patients With Depressive Symptoms: A Randomized Trial
    RE: Reducing Readmission of Hospitalized Patients With Depressive Symptoms: A Randomized Trial
    • Sydney P. Stein, Student, The Ohio State University
    • Other Contributors:
      • Melissa Garibotti, Student

    Those who struggle with depression often have difficulty performing everyday tasks and
    experience increased symptom burden. As such, as highlighted in Mitchell’s study, it is
    important to treat comorbid depression because of the associated physical and psychosocial
    health benefits which ultimately helps to lower hospital readmissions. Overall, compared to the
    control group (RED), patients randomly assigned to the RED-D protocol had fewer readmissions
    at 30 (receiving ≥ 3 sessions) and 90 (receiving ≥ 6 sessions) days post-discharge.

    The study flow chart clearly outlined patient eligibility and inclusion and exclusion criteria.
    However, it appears as though a significant number of patients needing additional follow-up
    care were not eligible for the study. Moving forward, we wonder what strategies can be
    implemented to successfully identify those at greatest risk (e.g., incarcerated) of readmission
    due to depression. An additional finding that stood out to us was the average age of study
    participants. In both groups, patients were approximately 50 year of age (50.3 years=RED-D
    and 50.9 years=RED). We are curious as to whether the research team feels as though the
    intervention would be as effective in younger patients as well. Thank you for conducting this
    study and we hope to learn more about your work in the future.

    Competing Interests: None declared.
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Reducing Readmission of Hospitalized Patients With Depressive Symptoms: A Randomized Trial
Suzanne E. Mitchell, Matthew Reichert, Jessica Martin Howard, Katherine Krizman, Alexa Bragg, Molly Huffaker, Kimberly Parker, Mary Cawley, Hannah Webb Roberts, Yena Sung, Jennifer Brown, Larry Culpepper, Howard J. Cabral, Brian W. Jack
The Annals of Family Medicine May 2022, 20 (3) 246-254; DOI: 10.1370/afm.2801

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Reducing Readmission of Hospitalized Patients With Depressive Symptoms: A Randomized Trial
Suzanne E. Mitchell, Matthew Reichert, Jessica Martin Howard, Katherine Krizman, Alexa Bragg, Molly Huffaker, Kimberly Parker, Mary Cawley, Hannah Webb Roberts, Yena Sung, Jennifer Brown, Larry Culpepper, Howard J. Cabral, Brian W. Jack
The Annals of Family Medicine May 2022, 20 (3) 246-254; DOI: 10.1370/afm.2801
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